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Search Results for " il 8 "

Targets Recommended: IL Receptor Caspase Interleukin

61

抑制剂 & 化合物

12

天然产物

2

化合物库

49

重组蛋白

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Cat. No.	Product Name
L3800	NF-κB 通路分子库		729 compounds
	729 个 NF-κB 信号通路相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
L7600	趋化因子抑制剂库		59 compounds
	59 种趋化因子或其受体抑制剂的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

NF-κB 通路分子库

Cat.No: L3800

Compounds: 729

趋化因子抑制剂库

Cat.No: L7600

Compounds: 59

Cat. No.	Product Name	Target	Signaling Pathways
T6761	Ossirene AS101	IL Receptor; Caspase; Interleukin	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Ossirene (AS101) 是一种免疫调节抑制剂，是一种新型 IL-1beta 转化酶抑制剂，可用于自身免疫性疾病和某些恶性肿瘤。它通过抑制IL-10消除 STAT3 的磷酸化，有效抑制Caspase-1。
T27695	JTE-607 JTE-607 dihydrochloride,JTE-607 HCl,甲氧番荔枝碱	Cysteine Protease	Proteases/Proteasome
	JTE-607 HCl 是高选择性的炎性细胞因子合成抑制剂，可保护小鼠免受内毒素休克。它作用于 LPS 刺激的人 PBMC，抑制TNF-α(IC50:11 nM)、IL-1β(IC50:5.9 nM)、IL-6(IC50:8.8 nM)、IL-8(IC50:7.3 nM)和IL-10(IC50:9.1 nM)。
T11179	Elubrixin SB-656933	IL Receptor; CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	Elubrixin (SB-656933) 是一种有效和特异性的 CXCR2 和 IL-8 受体拮抗剂。 Elubrixin 可用于炎症性疾病的研究，例如炎症性肠病和气道炎症。
T1497	Liranaftate Piritetrate,利拉萘酯,M-732	Antifungal	Microbiology/Virology
	Liranaftate (Piritetrate) 是一种具有抗真菌活性的硫代氨基甲酸酯和角鲨烯环氧酶抑制剂，可研究皮肤癣菌。
T3185	R112 (E)-Elafibranor	Syk	Angiogenesis; Tyrosine Kinase/Adaptors
	R112 ((E)-Elafibranor) 是ATP 竞争性的 Syk 激酶抑制剂，它能够抑制Syk 激酶活性，Ki=6 nM，IC50=226 nM。
T0089	Cetirizine dihydrochloride 盐酸西替利嗪,P071,UCB P071,Cetirizine DiHCl	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Cetirizine dihydrochloride (UCB P071) 是羟嗪的羧化代谢物，是特异性口服有效的 H1 受体长效拮抗剂。它标记抗过敏特性，抑制过敏反应期间嗜酸性粒细胞趋化，可有效治疗过敏性鼻炎、确诊荨麻疹和花粉诱发的哮喘。
T83712	Interleukin-8 (54-72) (human) TFA IL-8 (54-72),C-X-C Motif Chemokine Ligand (54-72),CXCL8 (54-72)
	Interleukin-8 (IL-8) (54-72) 对应于成熟人类IL-8序列的第54至72个氨基酸以及预处理序列的第81至99个氨基酸的肽。它抑制了初级人类中性粒细胞基于流动的黏附至人类脐静脉内皮细胞(HUVECs)。
T2036	6-OAU GTPL5846	GPR	Endocrinology/Hormones; GPCR/G Protein
	6-OAU (GTPL5846) 是 GPR84 的替代激动剂，在 Gqi5 嵌合体存在的情况下，在 HEK293 细胞中激活人 GPR84，在 PI 测定中 EC50 为 105 nM。
T6823	E3330	HIF/HIF Prolyl-Hydroxylase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	E3330 是一种口服有效的选择性 AP 内切核酸酶 1 (APE1; REF-1) 抑制剂，可抑制NF-κB DNA 结合活性。它阻断 TNF-α 诱导的肝癌细胞系中 IL-8 的激活，可以抑制癌细胞的生长和迁移，具有抗癌活性。
T1955	SB225002	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	SB225002 是一种有效的选择性 CXCR2 拮抗剂，抑制白介素 IL-8 与 CXCR2 的结合，IC50为 22 nM。
T39308	Boc-Asp(OMe)-fluoromethyl ketone Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK	Caspase	Apoptosis; Proteases/Proteasome
	Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) 是广谱的 caspase 抑制剂，可抑制 Fas 介导的吞噬作用和氧化破裂抑制，但对 IL-8 的趋化活性无影响。
T5193	Danirixin GSK1325756	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	Danirixin (GSK1325756) 是一种选择性可逆的CXCR2拮抗剂，抑制 CXCL8 的IC50值为 12.5 nM。
T24816	SP-100030 SP100030,SP 100030	NF-κB	NF-κB
	SP-100030 是一种有效的 NF-κB 和激活蛋白-1 (AP-1) 双抑制剂 (IC50 分别为 50 和 50 nM)。SP-10003 抑制 Jurkat 和其他T 细胞系产生的 IL-2、IL-8 和 TNF-α 的产生。SP-100030 降低小鼠胶原性关节炎 (CIA)。
T9656	AP-1/NF-κB activation inhibitor 1	NF-κB; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; NF-κB
	AP-1/NF-κB activation inhibitor 1 是一种有效的 AP-1和 NF-κB 介导的转录激活抑制剂(IC50=1 μM)，不阻断 β-actin 启动子驱动的基础转录。AP-1/NF-κB activation inhibitor 1 对受刺激细胞中 IL-2和 IL-8的产生水平有相似的抑制作用。
T76727	Teprotumumab R 1507,HZN 001	TSH Receptor; IGF-1R	GPCR/G Protein; Tyrosine Kinase/Adaptors
	Teprotumumab 是一种阻断 IGF-1 受体 (IGF-1R) 的人单克隆抗体。Teprotumumab 与 IGF-1R 的细胞外 α-亚基结构域配体结合。Teprotumumab 抑制纤维细胞中的 TSH 和 IGF-1 作用。Teprotumumab 可降低 TSH 依赖性 IL-6 和 IL-8 的表达和 Akt 的磷酸化。Teprotumumab 可用于甲状腺相关眼病的研究。
T38361	GSK717	IL Receptor; NOD	Immunology/Inflammation; NF-κB
	GSK717 是 NOD2(核苷酸结合寡聚结构域 2) 的选择性抑制剂。它抑制壁酰二肽 (MDP) 诱导的 NOD2 介导的信号转导，抑制 MDP 刺激的 HEK293/hNOD2 细胞分泌 IL-8 (IC50为 400 nM)。
T21644L	AF 12198 Acetate AF 12198 Acetate (185413-30-3 Free base)	IL Receptor	Immunology/Inflammation
	AF 12198 Acetate 是一种新型的低分子量 IL-1 拮抗剂。
T6488	Epinastine hydrochloride Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat	5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Epinastine hydrochloride (WAL-801CL HCl) 是抗组胺剂和肥大细胞稳定剂，是一种可口服的选择性组胺 H1 受体拮抗剂，可抑制 IL-8 释放，具有抗过敏作用。
TP1516L	C-Reactive Protein (CRP) 77-82 acetate C-Reactive Protein (CRP) 77-82 acetate(130349-01-8 free base)	Others	Others
	C-Reactive Protein (CRP) 77-82 acetate(130349-01-8 free base) 是 C-反应蛋白的 77-82 片段。 C-反应蛋白 (CRP) 是炎症的原型标志物，是心血管风险标志物，可能促进动脉粥样硬化。C-反应蛋白 (CRP) 是一种环状（环状）五聚体蛋白，存在于血浆中，其循环浓度炎症反应而升高。它是一种肝脏来源的急性期蛋白，在巨噬细胞和 T 细胞分泌 IL-6 后会增加。
T27967	M199
	M199, a novel inhibitor of TLR3/9 activation, induces secretion of IL-6, IL-8 and TNFalpha in human PBMCs.
T27708	K-14585
	K-14585 is a proteinase-activated receptor 2 antagonist. K-14585 inhibited PAR(2)-mediated p65 NFkappaB phosphorylation and NFkappaB-DNA binding. K-14585 inhibited SLIGKV-stimulated IL-8 production, but given alone increased IL-8.
T25469	GSK223 GSK 223,GSK-223
	GSK223 is an iE-DAP-stimulated IL-8 release inhibitor via the NOD1 signaling pathway.
T70001	Pyrazinib
	Pyrazinib is a novel inhibitor of angiogenesis and metabolism of oesophageal adenocarcinoma (oac) radioresistance, significantly inhibiting the secretion of il-6, il-4, il-8 and il-13 cytokines from in oac radioresistant cells
T80561	Atrosab
	Atrosab是一种人源化IgG1抗TNFR1抗体，具有拮抗作用。它能够抑制TNF诱导的细胞凋亡(apoptosis)，并减少IL-6和IL-8的生成，有助于研究炎症性疾病。
T35450	α-GalCer analog 8 α-GalCer analog 8,α-Galactosylceramide analog 8
	α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 &#181g per animal dose, indicati...
T63088	NOD2 antagonist 1
	NOD2 antagonist 1 (compound 32) 是一种有效的、选择性的 NOD2 拮抗剂 (IC50: 5.23 μM)。NOD2 antagonist 1 在 THP-1 细胞，对 Muramyl dipeptide (MDP) 诱导的 IL-8 分泌表现出抑制作用。NOD2 antagonist 1 在 PBMCs 细胞，可以抑制 MDP 诱导的 IL-6、IL-10 和 TNF-α 的水平升高。
T71048	Tacrolimus anhydrous 8-epimer
	Tacrolimus anhydrous 8-epimer is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2.
T36623	Antileukinate
	Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutrophils (Ki = 2.7-13 μM), prevents neutrophil chemotaxis and β-glucuronidase release, and blocks IL-8-induced skin edema in rabbits. At 53 mg/kg, antileukinate has been shown to protect mice against acute pancreatitis and associated lung injury.
T41189	AY 254
	AY 254 is a potent PAR2 biased agonist. Selectively activates ERK1/2 signaling (EC50= 2 nM for ERK1/2 phosphorylation versus 80 nM for Ca2+release). Reduces cytoKi ne-induced caspase 3/8 activation, promotes scratch-wound healing, and induces IL-8 secretion, in human colorectal cancer (HT29) cellsin vitro.
T2968L	Hyodeoxycholic acid sodium salt Sodium hyodeoxycholate,HDCA sodium
	Hyodeoxycholic acid sodium salt is a natural secondary bile acid. It improves high-density lipoprotein function, reduces farnesoid X receptor antagonist bile acids, and induces strong cytotoxicity, apoptosis, and IL-8 synthesis.
T80469	Citrullinated LL-37 1cit
	Citrullinated LL-37 1cit 是一种Citrullinated形式的 LL-37 肽，保持了针对 human rhinovirus 的抗病毒 (antiviral) 功能，同时对S. aureus 表现出抗菌 (antibacterial) 活性。此外，Citrullinated LL-37 1cit 能够降低 RV1B 诱导的 IL-8、CCL5 和 IL-6mRNA 水平。
TP2035	FSL-1 FSL 1
	TLR2/6 agonist (also a putative TLR10 ligand). Activates NF-κB. Induces pro-inflammatory cytokines including IL-8, IL-1β, CCL20 and TNF-α in vitro. Synergizes with IFNγ to induce CXCL10 release from melanoma cells.
T36198	Avenanthramide-C methyl ester
	Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Through this mechanism, avenanthramide-C methyl ester dose dependently inhibits the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells.
T76242	MMI-0100
	MMI-0100 是一种细胞渗透性肽抑制剂，抑制丝裂原活化蛋白激酶活化蛋白激酶 II (MK2)。MMI-0100 在体内外减少内膜增生。MMI-0100 抑制IL-6表达而不影响IL-8表达。MMI-0100 抑制纤维化过程，例如静脉移植疾病。
T78175	JAK-IN-25	JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	JAK-IN-25（化合物19）是一种高效的JAK抑制剂，对TYK2、JAK1、JAK2和JAK3的IC50值分别为6 nM、21 nM、8 nM、1051 nM。该化合物还能抑制人全血中IL-12（HEB IL-12），IC50为28 nM，显示其在癌症研究中的潜在应用价值。
T69599	ABT-510
	ABT-510 is synthetic peptide that mimics the anti-angiogenic activity of the endogenous protein thrombospondin-1 (TSP-1). ABT-510 inhibits the actions of several pro-angiogenic growth factors important to tumor neovascularization; these pro-angiogenic growth factors include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF)), hepatocyte growth factor (HGF), and interleukin 8 (IL-8).
T79256	DPP-4-IN-8
	DPP-4-IN-8 (compound 27) 是一种高效的选择性DPP4抑制剂，具有 0.96 μM 的 Ki。该化合物能够抑制 Caco-2 和 HepG-2 细胞中的 DPP4 二肽酶活性，并剂量依赖性地降低 TNF-α、IL-6 和 IL-1β 的表达水平[1]。
T60366	Epinastine
	Epinastine (WAL801) 是一种抗组胺剂和肥大细胞稳定剂。Epinastine 是一种有效的，选择性的，口服活性的组胺 H1 受体 (histamine H1 receptor) 拮抗剂。Epinastine 还抑制人嗜酸性粒细胞释放 IL-8 并具有抗过敏作用。
T62221	NLRP3-IN-8
	NLRP3-IN-8 (compound 27) 是具有口服活性的、与 NLRP3直接结合的 NLRP3炎性体抑制剂，对 IL-1β 的 IC50值为1.23 μM. NLRP3-IN-8 对肝微粒体具有良好的代谢稳定性 (t1/2= 138.63 min)，几乎没有毒性 (against L02: IC50> 100 μM) 。
T80470	Citrullinated LL-37 2cit
	Citrullinated LL-37 2cit是瓜氨酸化的LL-37肽，在10 μg/mL浓度下可减弱LL-37对HRV活性的抑制，并降低LL-37的抗菌效果。此外，Citrullinated LL-37 2cit能显著降低RV1B诱导的IL-8、CCL5和IL-6 mRNA水平，并对HRV诱导的CCL5分泌能力有中度抑制作用。
T38008	KBC-007
	KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at a concentration of 8 ng/ml. KBC-007 (1 μg per animal) increases levels of IL-4, but not IFN-γ, to a similar degree as α-GalCer in mouse serum. KBC-007 (0.5 μg per animal) increases the sur...
T61885	Sulconazole
	Sulconazole是一种咪唑类抗真菌剂，有效阻断NF-κB/IL-8信号通路和癌症干细胞(CSC)的形成，抑制肿瘤生长，适用于乳腺癌研究。
T76869	Lirentelimab
	Lirentelimab (AK002) 是一种人源化IgG1单克隆抗体，目标为唾液酸结合Ig样凝集素8 (SIGLEC8)。该化合物通过诱导IL-5激活的嗜酸性粒细胞细胞凋亡并抑制IL-5介导的肥大细胞激活，用于嗜酸性胃炎、十二指肠炎的研究。
T83798	8-bromo NAD+ sodium 8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+
	8-bromo NAD+ 作为循环ADP-核糖（cADPR）抑制剂8-bromo cADPR的前药形式，通过CD38转化为8-bromo-cADPR。在1 mM浓度下，8-bromo NAD+ 阻止由N-formyl-Met-Leu-Phe (fMLP) 在分离的小鼠骨髓衍生的中性粒细胞内引起的细胞内钙水平增加和趋化作用。同时，在100 µM浓度下使用，减少了小鼠原代小胶质细胞中LPS诱导的亚硝酸盐产生以及TNF-α和IL-2的分泌。
T83698	Cathelicidin-2 (128-153) (chicken) TFA Fowlicidin-2 (128-153),CATH-2 (128-153),Myeloid Antimicrobial Peptide 27 (128-153)
	Cathelicidin-2 (CATH-2) (128-153) 是一种合成抗菌肽，对应于鸡CATH-2的128至153个氨基酸。该化合物对E. coli、S. aureus、S. enteritidis和B. globigii展示出浓度依赖性的活性。CATH-2 (128-153) (40 µM) 可诱导孤立的鸡红细胞溶解，但对孤立的人外周血单个核细胞(PBMCs)无细胞毒性。它能促进化学因子(C-C-基序)配体2 (CCL2)的产生，并抑制LPS诱导的TNF-α、IL-6、IL-8和IL-10在孤立的人PBMCs中的产生。
T38360	NBC 19
	Potent NLRP3 inflammasome inhibitor (IC50 = 60-80 nM). Inhibits nigericin- and ATP-induced IL-1β release. Baldwin et al (2017) Boron-Based Inhibitors of the NLRP3 Inflammasome. Cell Chem.Biol. 24 1321 PMID:28943355 \|Redondo-Castro et al (2018) Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses. Sci.Rep. 8 5667 PMID:29618797
T83866	LCC-12 formate
	LCC-12是一种铜(II)螯合剂，为二甲双胍的衍生物。作为单体，它能结合铜(II)并在20 µM的浓度下减少氢过氧化物依赖的NADH向NAD+的氧化。在10 µM的浓度下，LCC-12降低一次性人类细胞因子激活的单核衍生的巨噬细胞(MDMs)中IL-1β、IL-2、IL-6、IL-8和TNF-α的细胞因子水平，以及JAK2、STAT2和IL-1受体相关激酶4(IRAK4)的水平。此外，同样浓度的LCC-12减少了细胞因子激活的MDMs中CD80+和CD86+的数量。每日0.3 mg/kg的剂量可提高LPS或盲肠结扎穿孔模型小鼠的存活率。
T41121	Elubrixin tosylate SB-656933 tosylate,Elubrixin tosylate
	Elubrixin tosylate (SB-656933 tosylate) is a high-potency, selective, competitive, and reversible CXCR2 antagonist, as well as an antagonist of the IL-8 receptor. It effectively inhibits upregulation of neutrophil CD11b (with an IC50 of 260.7 nM) and shape change (with an IC50 of 310.5 nM). This compound holds promise for the study of inflammatory diseases, including inflammatory bowel disease and airway inflammation.
T37564	C4 Ceramide (d18:1/4:0) C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)
	C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. [1] C4 Ceramide is cytotoxic to SK-BR-3 and MCF-7/Adr breast cancer cells (IC50s = 15.9 and 19.9 μM, respectively). [2] C4 Ceramide also increases maturation and stability of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing...
T21633	N-3-oxo-dodecanoyl-L-Homoserine lactone
	N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) 是由铜绿假单胞菌和洋葱状芽孢杆菌复合物菌株产生的细菌群体感应信号分子，群体感应是细菌用来控制基因表达以响应细胞密度增加的调节系统。N-3-oxo-dodecanoyl-L-Homoserine lactone 诱导 16HBE 人支气管上皮细胞产生 IL-8。

化合物

Cat.No: T6761

Synonym: AS101

Target: IL Receptor, Caspase, Interleukin

Cat.No: T27695

Synonym: JTE-607 dihydrochloride,JTE-607 HCl,甲氧番荔枝碱

Target: Cysteine Protease

Cat.No: T11179

Synonym: SB-656933

Target: IL Receptor, CXCR

Cat.No: T1497

Synonym: Piritetrate,利拉萘酯,M-732

Target: Antifungal

Cat.No: T3185

Synonym: (E)-Elafibranor

Target: Syk

Cetirizine dihydrochloride

Cat.No: T0089

Synonym: 盐酸西替利嗪,P071,UCB P071,Cetirizine DiHCl

Target: Histamine Receptor

Interleukin-8 (54-72) (human) TFA

Cat.No: T83712

Synonym: IL-8 (54-72),C-X-C Motif Chemokine Ligand (54-72),CXCL8 (54-72)

Cat.No: T2036

Synonym: GTPL5846

Target: GPR

Cat.No: T6823

Target: HIF/HIF Prolyl-Hydroxylase, DNA/RNA Synthesis

Cat.No: T1955

Target: CXCR

Boc-Asp(OMe)-fluoromethyl ketone

Cat.No: T39308

Synonym: Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK

Target: Caspase

Cat.No: T5193

Synonym: GSK1325756

Target: CXCR

Cat.No: T24816

Synonym: SP100030,SP 100030

Target: NF-κB

AP-1/NF-κB activation inhibitor 1

Cat.No: T9656

Target: NF-κB, DNA/RNA Synthesis

Cat.No: T76727

Synonym: R 1507,HZN 001

Target: TSH Receptor, IGF-1R

Cat.No: T38361

Target: IL Receptor, NOD

AF 12198 Acetate

Cat.No: T21644L

Synonym: AF 12198 Acetate (185413-30-3 Free base)

Target: IL Receptor

Epinastine hydrochloride

Cat.No: T6488

Synonym: Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat

Target: 5-HT Receptor, Histamine Receptor

C-Reactive Protein (CRP) 77-82 acetate

Cat.No: TP1516L

Synonym: C-Reactive Protein (CRP) 77-82 acetate(130349-01-8 free base)

Target: Others

Cat.No: T27967

Cat.No: T27708

Cat.No: T25469

Synonym: GSK 223,GSK-223

Cat.No: T70001

Cat.No: T80561

α-GalCer analog 8

Cat.No: T35450

Synonym: α-GalCer analog 8,α-Galactosylceramide analog 8

NOD2 antagonist 1

Cat.No: T63088

Tacrolimus anhydrous 8-epimer

Cat.No: T71048

Cat.No: T36623

Cat.No: T41189

Hyodeoxycholic acid sodium salt

Cat.No: T2968L

Synonym: Sodium hyodeoxycholate,HDCA sodium

Citrullinated LL-37 1cit

Cat.No: T80469

Cat.No: TP2035

Synonym: FSL 1

Avenanthramide-C methyl ester

Cat.No: T36198

Cat.No: T76242

Cat.No: T78175

Target: JAK

Cat.No: T69599

Cat.No: T79256

Cat.No: T60366

Cat.No: T62221

Citrullinated LL-37 2cit

Cat.No: T80470

Cat.No: T38008

Cat.No: T61885

Cat.No: T76869

8-bromo NAD+ sodium

Cat.No: T83798

Synonym: 8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+

Cathelicidin-2 (128-153) (chicken) TFA

Cat.No: T83698

Synonym: Fowlicidin-2 (128-153),CATH-2 (128-153),Myeloid Antimicrobial Peptide 27 (128-153)

Cat.No: T38360

Cat.No: T83866

Elubrixin tosylate

Cat.No: T41121

Synonym: SB-656933 tosylate,Elubrixin tosylate

C4 Ceramide (d18:1/4:0)

Cat.No: T37564

Synonym: C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)

N-3-oxo-dodecanoyl-L-Homoserine lactone

Cat.No: T21633

Cat. No.	Product Name	Target	Signaling Pathways
TN1520	Isoforskolin Coleonol B	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Isoforskolin 源自毛喉鞘蕊花，可减少人单核白细胞中 TNF-α、IL-1β、IL-6 和 IL-8 的分泌。Isoforskolin 可用于治疗莱姆关节炎的研究。
T5680	Aloin(mixture of A&B) 芦荟素,葡糖基蒽酮,芦荟大黄素甙,芦荟苷	MMP; IL Receptor; Antibacterial; Antifungal	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Aloin (mixture of A&B) 是一种从芦荟中分离出来的蒽醌衍生物。它是刺激性粒细胞基质金属蛋白酶的有效抑制剂。它具有多种生物活性，如抗炎、抗菌、抗真菌、抗氧化、抗肿瘤、抗糖尿病和免疫活性。
T4S0795	Berberrubine chloride 9-Berberoline Chloride,Beroline,Beroline Chloride,小檗红碱,Berberrubine,9-Berberoline	IL Receptor	Immunology/Inflammation
	Berberrubine chloride (9-Berberoline Chloride) 是一种黄连素的有效代谢物，能够改善动物模型中溃疡性结肠炎的症状。
T2791	Pectolinarin 柳穿鱼叶苷,大蓟苷	Apoptosis; Others; NO Synthase; Prostaglandin Receptor; Interleukin	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Others
	Pectolinarin 抑制 IL-6和 IL-8分泌以及 PGE2和 NO 产生，可通过抑制 PI3K/Akt 途径来抑制细胞增殖和炎症反应并诱导凋亡，具有抗炎活性。
TN1154	Nepetin 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素	Calcium Channel; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Nepetin (6-Methoxyluteolin) 是一种分离自Eupatorium ballotaefoliumHBK 中的天然类黄酮，具有有效的抗炎作用。它在 ARPE-19 细胞中能够抑制IL-6(IC50:4.43 μM) 、IL-8 (IC50:43.42 μM) 、MCP-1 (IC50:4.17 μM) 的分泌。
T3398	Icaritin Anhydroicaritin,去水淫羊藿黄素,Cycloicaritin	Apoptosis; JAK; STAT; Autophagy	Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	Icaritin (Anhydroicaritin) 是Epimedium Genusis 的异戊二烯类黄酮衍生物，有效抑制 K562 细胞和原代 CML 细胞的增殖。它可以调节MAPK/ERK/JNK 和JAK2/STAT3/AKT 信号传导，并具有增强成骨的作用。
T4115	Auraptene 橙皮油内酯,7-geranyloxycoumarin,橙皮油素	MMP; BACE	Neuroscience; Proteases/Proteasome
	Auraptene 是一种丰富的天然香叶氧基香豆素。它能够抑制基质金属蛋白酶 2 以及关键炎症因子，包括 IL-6，IL-8 和趋化因子 (C-C 基序) 配体-5 (CCL5）的分泌。
T75674	Pedunculagin
	Pedunculagin为有效的1型5α-还原酶抑制剂，能抑制一氧化氮(NO)、IL-6、IL-8产生，并降低5α-reductase蛋白质表达，具抗炎活性。
TN5238	Viscidulin II	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of viscidulin II with P. acnes can effectively attenuate P. acnes-induced ear swelling, and decrease the production of IL-6 and tumor necrosis factor-α in ear homogenates.
T75694	Lacto-N-neotetraose
	Lacto-N-neotetraose (LNnT) 是一种内源性代谢物 (endogenous metabolite)。Lacto-N-neotetraose 可以抑制 TNF-α 诱导的未成熟上皮细胞中的IL-8分泌。Lacto-N-neotetraose 具有抗炎活性，可提高伤口愈合能力。
T37751	Streptazolin
	Streptazolin is a fungal metabolite originally isolated from S. viridochromogenes. It increases NF-κB activity when used at concentrations ranging from 60 to 130 μg/ml, at least in part, via PI3K signaling. Streptazolin enhances TNF-α secretion induced by LPS and enhances IL-8 secretion when used alone or in combination with LPS in THP-1 Blue cells.
TN4471	Lysicamine	IL Receptor; Antifection	Immunology/Inflammation; Microbiology/Virology
	Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and anti-inflammation activity, the mini

天然产物

Cat.No: TN1520

Synonym: Coleonol B

Target: IL Receptor, TNF

Aloin(mixture of A&B)

Cat.No: T5680

Synonym: 芦荟素,葡糖基蒽酮,芦荟大黄素甙,芦荟苷

Target: MMP, IL Receptor, Antibacterial, Antifungal

Berberrubine chloride

Cat.No: T4S0795

Synonym: 9-Berberoline Chloride,Beroline,Beroline Chloride,小檗红碱,Berberrubine,9-Berberoline

Target: IL Receptor

Cat.No: T2791

Synonym: 柳穿鱼叶苷,大蓟苷

Target: Apoptosis, Others, NO Synthase, Prostaglandin Receptor, Interleukin

Cat.No: TN1154

Synonym: 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素

Target: Calcium Channel, Histamine Receptor

Cat.No: T3398

Synonym: Anhydroicaritin,去水淫羊藿黄素,Cycloicaritin

Target: Apoptosis, JAK, STAT, Autophagy

Cat.No: T4115

Synonym: 橙皮油内酯,7-geranyloxycoumarin,橙皮油素

Target: MMP, BACE

Cat.No: T75674

Cat.No: TN5238

Target: IL Receptor, TNF

Lacto-N-neotetraose

Cat.No: T75694

Cat.No: T37751

Cat.No: TN4471

Target: IL Receptor, Antifection

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04726	IL-8/CXCL8 Protein, Human, Recombinant (His) Interleukin-8,GCP1,MONAP,LECT,LYNAP,NAF,GCP-1,LUCT,...	Human	P. pastoris (Yeast)
	IL-8/CXCL8 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.8 kDa and the accession number is A0A024RDA5.
TMPY-00472	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99) NAF,GCP1,NAP1,chemokine (C-X-C motif) ligand 8,Inte...	Human	E. coli
	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99) is expressed in E. coli expression system. The predicted molecular weight is 8.5 kDa and the accession number is A0A024RDA5.
TMPY-00754	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99) MONAP,MDNCF,NAP-1,白介素,NAP1,LUCT,chemokine (C-X-C motif) liga...	Human	HEK293 Cells
	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99) is expressed in HEK293 mammalian cells. The predicted molecular weight is 8 kDa and the accession number is A0A024RDA5.
TMPJ-01172	IL-17 Protein, Mouse, Recombinant (His) CTLA8,IL-17,IL-17A,Interleukin-17...	Mouse	HEK293 Cells
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumato...
TMPY-02886	IL-17A Protein, Human, Recombinant IL-17,白细胞介素,interleukin 17A,CTLA8,白介素,...	Human	E. coli
	IL-17A Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552.
TMPY-00470	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His) interleukin 17A,IL-17,IL-17A,IL17...	Human	HEK293 Cells
	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is NP_002181.1&NP_443104.1.
TMPY-00053	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant CTLA8,IL17,IL-17,IL-17A,...	Human	E. coli
	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30.7 kDa and the accession number is Q16552&NP_443104.1.
TMPY-02900	IL-17A Protein, Mouse, Recombinant IL-17A,Ctla8,Ctla-8,interleukin 1...	Mouse	E. coli
	IL-17A Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.5 kDa and the accession number is Q62386.
TMPK-00480	IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His) GCP/IL-8 protein IV,MDNCF,CXCL8,G...	Cynomolgus	HEK293 Cells
	Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several promising approaches that target directly or indirectly IL-8 effects in gliomas are currently in progress while more-in-depth studies are needed to validate its biomarker role and elucidate the underlying molecular mechanisms.
TMPY-00753	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc) LECT,MONAP,IL-8,LYNAP,白细胞介素,chemokine (C-X...	Human	HEK293 Cells
	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.6 kDa and the accession number is A0A024RDA5.
TMPY-00755	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc) chemokine (C-X-C motif) ligand 8,Interleukin-8<...	Human	HEK293 Cells
	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDA5.
TMPK-01036	IL-17A Protein, Mouse, Recombinant (His & Avi) interleukin 17A,IL17A,CTLA-8,IL17...	Mouse	HEK293 Cells
	IL-17A Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1.
TMPK-01266	IL-17A Protein, Cynomolgus, Recombinant (His & Avi) IL17,interleukin 17A,IL17A,IL-17C...	Cynomolgus	HEK293 Cells
	IL-17A Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is A0A2K5TTB0.
TMPK-00975	IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated IL-17CTLA-8,interleukin 17A,CTLA-8	Human	HEK293 Cells
	IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is Q16552-1.
TMPK-01037	IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated IL17A,interleukin 17A,IL17,CTLA-8...	Mouse	HEK293 Cells
	IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1.
TMPK-01045	IL-20RA Protein, Mouse, Recombinant (hFc) IL-20R1,CRF2-8,IL-20R-alpha,I...	Mouse	HEK293 Cells
	IL-20RA was highly expressed in the tumor tissue of CRC and related to the advanced stage.IL-20RA was involved in regulating oncogenic and immune pathways and affecting the expression of genes related to cell proliferation and immune evasion in CRC.Super-enhancer inhibition by JQ-1 or iBET-151 suppressed the growth of tumor cells and inhibited the expression of IL-20RA.
TMPJ-01444	IL-17A Protein, Cynomolgus, Recombinant (His) CTLA-8,CTLA8,IL17A,IL-17...	Cynomolgus	HEK293 Cells
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synt...
TMPY-04332	IL-17A Protein, Human, Recombinant (T26A, His) CTLA-8,CTLA8,IL-17A,interleukin 1...	Human	Baculovirus Insect Cells
	IL-17A Protein, Human, Recombinant (T26A, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.2 kDa and the accession number is Q16552.
TMPY-05183	IL-17A Protein, Human, Recombinant, Biotinylated interleukin 17A,IL-17,白细胞介素,白介素,IL17,CTLA<...	Human	E. coli
	IL-17A Protein, Human, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552.
TMPY-03568	IL-17A Protein, Human, Recombinant (His) CTLA-8,CTLA8,白介素,interleukin 17A,IL	Human	P. pastoris (Yeast)
	IL-17A Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 17.3 kDa and the accession number is Q16552.
TMPY-00280	IL-20RA Protein, Human, Recombinant (hFc) interleukin 20 receptor, α,IL-20R-α,interleukin 20 ...	Human	HEK293 Cells
	IL-20RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is Q9UHF4-1.
TMPY-01054	IL-20RA Protein, Human, Recombinant (His) IL-20R1,IL-20R-α,CRF2-8,interleuk...	Human	HEK293 Cells
	IL-20RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9UHF4-1.
TMPH-00376	IL-8/CXCL8 Protein, Chicken, Recombinant	Chicken	E. coli
	May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. IL-8/CXCL8 Protein, Chicken, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.4 kDa and the accession number is P08317.
TMPY-03480	IL-8/CXCL8 Protein, Rhesus, Recombinant 白介素,chemokine (C-X-C motif) ligand 8,白细胞介素	Rhesus	E. coli
	IL-8/CXCL8 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.3 kDa and the accession number is P67813.
TMPY-03022	IL-8/CXCL8 Protein, Canine, Recombinant chemokine (C-X-C motif) ligand 8	Canine	E. coli
	IL-8/CXCL8 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.2 kDa and the accession number is P41324.
TMPH-00375	IL-8/CXCL8 Protein, Chicken, Recombinant (His)	Chicken	E. coli
	May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. IL-8/CXCL8 Protein, Chicken, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 13.4 kDa and the accession number is P08317.
TMPY-02583	IL-1F8 Protein, Mouse, Recombinant RP23-176J12.1,interleukin 36, β,Il36b,2310043N20Rik...	Mouse	E. coli
	IL-1F8 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21 kDa and the accession number is Q9D6Z6.
TMPY-02458	IL-1F8 Protein, Human, Recombinant FILI-(ETA),FIL1-(ETA),IL-1H2,...	Human	E. coli
	IL-1F8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa and the accession number is Q9NZH7-2.
TMPY-02817	IL-1F8 Protein, Human, Recombinant (His) FIL1,FIL1H,IL1-ETA,interleukin 36...	Human	E. coli
	IL-1F8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 19.3 kDa and the accession number is Q9NZH7-2.
TMPJ-00994	LTBR Protein, Mouse, Recombinant (hFc) Tnfcr,Lymphotoxin-beta receptor,Tumor necrosis factor recept...	Mouse	HEK293 Cells
	It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs...
TMPH-01559	IL-26 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. IL-26 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecula...
TMPY-04123	CEACAM1 Protein, Human, Recombinant (His & hFc) CEACAM‑1,carcinoembryonic antigen-related cell adhesion mole...	Human	HEK293 Cells
	CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8.
TMPH-01560	IL-26 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. IL-26 Protein, Human, Recombinant (His & Trx) is expressed in E. coli expression system with N-6xHis-T...
TMPK-00405	IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated IL-7R-alpha,IL-7R,ILRA,IL	Human	HEK293 Cells
	Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22.
TMPJ-01237	IL-17D Protein, Human, Recombinant IL17D,Interleukin-17D,IL-17D	Human	E. coli
	The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. IL-17 family proteins are proinflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Among IL-17 family members, IL-17D is most closely related to IL-17B, sharing 27% aa sequence ho...
TMPJ-01060	CXCL6 Protein, Human, Recombinant (His) SCYB6,Chemokine Alpha 3,CKA-3,GCP2,GCP-2,C-X-C Motif Chemoki...	Human	HEK293 Cells
	Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell...
TMPJ-01361	Siglec-8 Protein, Human, Recombinant (mFc) CD329 antigen,Siglec-8,SAF2SAF-2,CDw329,Siglec8...	Human	HEK293 Cells
	Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Siglec-8 is expressed on eosinophils, basophils, and mast cells, and it shows a binding preference for the carbohydrate 6-O sulfated sLex. At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Mature human Siglec-8 c...
TMPJ-00060	IL-25/IL17E Protein, Human, Recombinant (His) 白细胞介素,IL17E,白介素,IL-17E,IL-25,...	Human	HEK293 Cells
	Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a non-covalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL-17 family proteins are pro-inflammator...
TMPY-03853	DCBLD2 Protein, Human, Recombinant (His) CLCP1,discoidin, CUB and LCCL domain containing 2,ESDN	Human	HEK293 Cells
	DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that is known to regulate IL-8 production in human lung fibroblasts and epithelial cells. DCBLD2 could be related to FEV(1)-related phenotypes in asthmatics. DCBLD2 gene is expressed at very high level. DCBLD2 is proposed to participate in processes such as intracellular receptor med...
TMPJ-01187	Siglec-E Protein, Mouse, Recombinant (hFc) SiglecE,Siglec-E	Mouse	HEK293 Cells
	Siglecs are sialic acid specific I‑type lectins that are characterized by an extracellular domain (ECD) with an N‑terminal Ig‑like V‑set domain followed by varying numbers of Ig‑like C2‑set domains. Mouse Siglec‑E, also known as Myeloid Inhibitory Siglec (MIS), is an 80 ‑ 85 kDa member of the CD33‑related subfamily of Siglecs. Rodent and primate Siglec gene families have significantly diverged, and Siglec‑9 is the most likely human ortholog of mouse Siglec‑E. Siglec‑E is expressed as a heavily N...
TMPJ-00760	CXCL7 Protein, Human, Recombinant SCYB7,C-X-C Motif Chemokine 7,Leukocyte-Derived Growth Facto...	Human	E. coli
	Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domain containing CXC chemokines, such as IL-8 and the GRO proteins, CXCL7 binds CXCR2, chemoattracts and activates neutrophils. CXCL7, Connective Tissue Activating Protein III (CTAPIII) and βthrombogulin (βTG), are proteolytically processed carboxylterminal fragments of platelet basi...
TMPY-02893	NT5C3A/NT5C3 Protein, Human, Recombinant P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN1,UMPH1,UMPH,POMP,5'-nucleo...	Human	E. coli
	NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but...
TMPH-01705	Mucin-1/MUC1 Protein, Human, Recombinant (His)	Human	E. coli
	Mucin-1/MUC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.2 kDa and the accession number is P15941-8.
TMPJ-00808	CD45RA Protein, Human, Recombinant (His) PTPRC,CD45R,CD45,LCA,protein tyrosine phosphatase, receptor ...	Human	HEK293 Cells
	CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8.
TMPJ-00828	Tau-F Protein, Human, Recombinant Neurofibrillary tangle protein,Paired helical f...	Human	E. coli
	Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. The tau proteins are the product of alternative splicing from a single gene that in humans is designated MAPT. When tau proteins are def...
TMPY-00717	CEACAM1 Protein, Human, Recombinant (His) CEACAM‑1,BGP1,BGP,carcinoembryonic antigen-related cell adhe...	Human	HEK293 Cells
	CEACAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.8 kDa and the accession number is P13688-8.
TMPY-06707	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) ADMCKD,PEMT,KL-6,ADMCKD1,H23AG,mucin 1, cell surface associa...	Human	HEK293 Cells
	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.49 kDa and the accession number is P15941-8.
TMPJ-01330	CD299 Protein, Human, Recombinant (His & Flag) DC-SIGNR,L-SIGN,CD299,CD209L,LSIGN,C-type lectin domain fam<...	Human	HEK293 Cells
	CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-SIGN/CD209 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGNR is ragarded as a pathogen-recognition receptor involved in peripheral immune surveillance in liver, and probably mediate the endocytosis of pathogens which are subsequently degraded in lysoso...
TMPY-00668	APP/Protease nexin-II Protein, Human, Recombinant (hFc) CTFγ,amyloid beta (A4) precursor protein,AAA,ABPP,CVAP,APPI,...	Human	HEK293 Cells
	APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.

重组蛋白

IL-8/CXCL8 Protein, Human, Recombinant (His)

Cat.No: TMPY-04726

Species: Human

Expression System: P. pastoris (Yeast)

IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99)

Cat.No: TMPY-00472

Species: Human

Expression System: E. coli

IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99)

Cat.No: TMPY-00754

Species: Human

Expression System: HEK293 Cells

IL-17 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01172

Species: Mouse

Expression System: HEK293 Cells

IL-17A Protein, Human, Recombinant

Cat.No: TMPY-02886

Species: Human

Expression System: E. coli

IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His)

Cat.No: TMPY-00470

Species: Human

Expression System: HEK293 Cells

IL-17A & IL-17F Heterodimer Protein, Human, Recombinant

Cat.No: TMPY-00053

Species: Human

Expression System: E. coli

IL-17A Protein, Mouse, Recombinant

Cat.No: TMPY-02900

Species: Mouse

Expression System: E. coli

IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00480

Species: Cynomolgus

Expression System: HEK293 Cells

IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc)

Cat.No: TMPY-00753

Species: Human

Expression System: HEK293 Cells

IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc)

Cat.No: TMPY-00755

Species: Human

Expression System: HEK293 Cells

IL-17A Protein, Mouse, Recombinant (His & Avi)

Cat.No: TMPK-01036

Species: Mouse

Expression System: HEK293 Cells

IL-17A Protein, Cynomolgus, Recombinant (His & Avi)

Cat.No: TMPK-01266

Species: Cynomolgus

Expression System: HEK293 Cells

IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00975

Species: Human

Expression System: HEK293 Cells

IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01037

Species: Mouse

Expression System: HEK293 Cells

IL-20RA Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-01045

Species: Mouse

Expression System: HEK293 Cells

IL-17A Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-01444

Species: Cynomolgus

Expression System: HEK293 Cells

IL-17A Protein, Human, Recombinant (T26A, His)

Cat.No: TMPY-04332

Species: Human

Expression System: Baculovirus Insect Cells

IL-17A Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-05183

Species: Human

Expression System: E. coli

IL-17A Protein, Human, Recombinant (His)

Cat.No: TMPY-03568

Species: Human

Expression System: P. pastoris (Yeast)

IL-20RA Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00280

Species: Human

Expression System: HEK293 Cells

IL-20RA Protein, Human, Recombinant (His)

Cat.No: TMPY-01054

Species: Human

Expression System: HEK293 Cells

IL-8/CXCL8 Protein, Chicken, Recombinant

Cat.No: TMPH-00376

Species: Chicken

Expression System: E. coli

IL-8/CXCL8 Protein, Rhesus, Recombinant

Cat.No: TMPY-03480

Species: Rhesus

Expression System: E. coli

IL-8/CXCL8 Protein, Canine, Recombinant

Cat.No: TMPY-03022

Species: Canine

Expression System: E. coli

IL-8/CXCL8 Protein, Chicken, Recombinant (His)

Cat.No: TMPH-00375

Species: Chicken

Expression System: E. coli

IL-1F8 Protein, Mouse, Recombinant

Cat.No: TMPY-02583

Species: Mouse

Expression System: E. coli

IL-1F8 Protein, Human, Recombinant

Cat.No: TMPY-02458

Species: Human

Expression System: E. coli

IL-1F8 Protein, Human, Recombinant (His)

Cat.No: TMPY-02817

Species: Human

Expression System: E. coli

LTBR Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00994

Species: Mouse

Expression System: HEK293 Cells

IL-26 Protein, Human, Recombinant (His)

Cat.No: TMPH-01559

Species: Human

Expression System: P. pastoris (Yeast)

CEACAM1 Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-04123

Species: Human

Expression System: HEK293 Cells

IL-26 Protein, Human, Recombinant (His & Trx)

Cat.No: TMPH-01560

Species: Human

Expression System: E. coli

IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated

Cat.No: TMPK-00405

Species: Human

Expression System: HEK293 Cells

IL-17D Protein, Human, Recombinant

Cat.No: TMPJ-01237

Species: Human

Expression System: E. coli

CXCL6 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01060

Species: Human

Expression System: HEK293 Cells

Siglec-8 Protein, Human, Recombinant (mFc)

Cat.No: TMPJ-01361

Species: Human

Expression System: HEK293 Cells

IL-25/IL17E Protein, Human, Recombinant (His)

Cat.No: TMPJ-00060

Species: Human

Expression System: HEK293 Cells

DCBLD2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03853

Species: Human

Expression System: HEK293 Cells

Siglec-E Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-01187

Species: Mouse

Expression System: HEK293 Cells

CXCL7 Protein, Human, Recombinant

Cat.No: TMPJ-00760

Species: Human

Expression System: E. coli

NT5C3A/NT5C3 Protein, Human, Recombinant

Cat.No: TMPY-02893

Species: Human

Expression System: E. coli

Mucin-1/MUC1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01705

Species: Human

Expression System: E. coli

CD45RA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00808

Species: Human

Expression System: HEK293 Cells

Tau-F Protein, Human, Recombinant

Cat.No: TMPJ-00828

Species: Human

Expression System: E. coli

CEACAM1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00717

Species: Human

Expression System: HEK293 Cells

Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)

Cat.No: TMPY-06707

Species: Human

Expression System: HEK293 Cells

CD299 Protein, Human, Recombinant (His & Flag)

Cat.No: TMPJ-01330

Species: Human

Expression System: HEK293 Cells

APP/Protease nexin-II Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00668

Species: Human

Expression System: HEK293 Cells

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